Hon. Bishop (Emeritus) Dr. Zephania Kameeta attended the Martin Luther High School at Okombahe and then the Paulinum Seminary at Otjimbingwe (1968–1971). He was ordained as a Minister of the Evangelical Lutheran Church in Namibia in 1972, and taught at the Paulinium Seminary, at Otjimbingwe, from 1973, and was principal 1976-77.
Hon. Kameeta, was a parish minister in Lüderitz from 1978 to 1981. He was elected vice-president of the Evangelical Lutheran Church in 1982 and deputy Bishop in 1985. He was an exponent of Black Theology. Between 2002 and 2013 Hon. Kameeta served as the Bishop of the Evangelical Lutheran Church in the Republic of Namibia (ELCRN).
Hon. Kameeta was actively involved in the Namibian liberation struggle, led by the South West Africa People's Organization (SWAPO). He was a member of the SWAPO party Central Committee and Politburo. In 1975, he was arrested and detained under the Terrorist Act. When Namibia became independent, he was elected as a SWAPO member of the National Assembly, and became the first Deputy Speaker of the National Assembly.
Between 2008-2010, Hon. Kameeta led the Basic Income Grant Coalition that piloted the World renowned Basic Income Grant at Omitara Village in Namibian Eastern Region of Omaheke. On Heroes' Day in 2014 Hon. Kameeta was conferred the Most Brilliant Order of the Sun, First Class. Hon. Kameeta is married to Mrs. Elizabeth Kameeta and together they have five children.
Hon. Bishop (Emeritus) Dr. Zephania Kameeta became the first Minister of the newly created Ministry of Poverty Eradication and Social Welfare, on the dawn of the 21st March 2015.